TY  - BOOK
ED  - Le, Anne
AB  - This open access volume will introduce recent discoveries in cancer metabolism since the publication of the first edition in 2018, providing readers with an up-to-date understanding of developments in the field. Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, the authors delve into the complexity and diversity of cancer metabolism and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies for cancer treatment. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer treatment. This book has four major parts. Part one will cover the basic metabolism of cancer cells, followed by a discussion of the heterogeneity of cancer metabolism in part two. Part three addresses the relationship between cancer cells and cancer-associated fibroblasts, and the new part four will explore the metabolic interplay between cancer and other diseases. This new section makes the book unique from other texts currently available on the market. The second edition will be useful for cancer metabolism researchers, cancer biologists, epidemiologists, physicians, health care professionals in related disciplines, policymakers, marketing and economic strategists, among others. It may also be used in courses such as intro to cancer metabolism, cancer biology, and related biochemistry courses for undergraduate and graduate students.
DO  - 10.1007/978-3-030-65768-0
ID  - OAPEN ID: ONIX_20210614_9783030657680_24
KW  - Cancer Research
KW  - Cancer Metabolism
KW  - Cancer Therapy
KW  - Cancer Biology
KW  - open access
KW  - personalized cancer treatment
KW  - glucose metabolism
KW  - glutamine metabolism
KW  - metabolism biomarkers
KW  - metabolic pathways
KW  - drug treatments
KW  - glioblastoma
KW  - pancreatic cancer
KW  - breast cancer
KW  - renal cell carcinoma
KW  - non-hodgkin's lymphoma
KW  - cancer-associated fibroblasts
KW  - tumor microenvironment
KW  - covid-19
KW  - diabetes
KW  - cardiovascular diseases
KW  - gene profiles
KW  - chemotherapeutic agenet
KW  - clinical trials
KW  - Oncology
L1  - https://library.oapen.org/bitstream/id/69aece39-d2a9-4f24-bff1-b320d50362c7/9783030657680.pdf
LA  - English
LK  - https://library.oapen.org/handle/20.500.12657/49522
PB  - Springer Nature
PY  - 2021
SN  - 9783030657680
TI  - The Heterogeneity of Cancer Metabolismnull
ER  - 
