Chapter 11 Metabolomics in the Analysis of Inflammatory Diseases

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Author(s)
Clay, Elizabeth
Kapoor, Sabrina
Bayley, Rachel
Wallace, Graham R.
Young, Stephen P.
Fitzpatrick, Martin
Kapoor, Sabrina
Fitzpatrick, Martin
Clay, Elizabeth
Bayley, Rachel
R., Graham
P., Stephen
Collection
Wellcome
Language
English
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Abstract
Most infections and traumatic injuries are cleared or repaired relatively rapidly and metabolic homoeostasis is soon restored. However, there is a broad range of inflammatory diseases which involve chronic activation of the immune system and, as a result, chronic persistent inflammation. We have been studying the metabolic consequences of chronic inflammatory diseases with the aim of identifying metabolic fingerprints which may provide clues about why the localised tissue disease persists.
Book
Metabolomics
URI
http://library.oapen.org/handle/20.500.12657/31533
Keywords
molecular biology; biochemistry; genetics; molecular biology; biochemistry; genetics; Hypoxia (medical); Inflammation; Lactic acid; Metabolism; Metabolite; Metabolomics; Rheumatoid arthritis
DOI
10.5772/31814
OCN
1030822503
Publisher
InTechOpen
Publisher website
https://www.intechopen.com/
Publication date and place
2012
Grantor
Classification
Biochemistry
Public remark
Relevant Wikipedia pages: Hypoxia (medical) - https://en.wikipedia.org/wiki/Hypoxia_(medical); Inflammation - https://en.wikipedia.org/wiki/Inflammation; Lactic acid - https://en.wikipedia.org/wiki/Lactic_acid; Metabolism - https://en.wikipedia.org/wiki/Metabolism; Metabolite - https://en.wikipedia.org/wiki/Metabolite; Metabolomics - https://en.wikipedia.org/wiki/Metabolomics; Rheumatoid arthritis - https://en.wikipedia.org/wiki/Rheumatoid_arthritis
Rights
https://creativecommons.org/licenses/by/3.0/