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dc.contributor.authorPaterson, Martin J.
dc.contributor.authorBergendahl, L. Therese
dc.date.accessioned2019-10-04 14:33:32
dc.date.accessioned2020-04-01T14:06:53Z
dc.date.accessioned2016-08-01 23:55
dc.date.accessioned2019-10-04 14:33:32
dc.date.accessioned2020-04-01T14:06:53Z
dc.date.accessioned2016-12-31 23:55:55
dc.date.accessioned2019-10-04 14:33:32
dc.date.accessioned2020-04-01T14:06:53Z
dc.date.available2020-04-01T14:06:53Z
dc.date.issued2012
dc.identifier612605
dc.identifier.urihttp://library.oapen.org/handle/20.500.12657/32338
dc.description.abstractPhotodynamic therapy (PDT) is a branch of phototherapy that has seen a surge of interest in the last few decades, due to its potential in the treatment of various cancers, infections and heart disease.(Bonnett, 2000) This chapter aims to give an overview of the various photochemical steps involved in PDT as a cancer therapy, and in particular the challenges and insight gained from their theoretical description. After a brief review of PDT in general, in a biological and chemical context, the photochemical steps involved will be discussed, detailing the computational techniques required to model these chemical pathways theoretically. We will detail the methodologies that can currently be applied, as well as their limitations of use at present, and areas requiring further development.
dc.languageEnglish
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PD Science: general issues
dc.subject.othercomputational modelling
dc.subject.otherphotodynamic therapy
dc.subject.othercomputational modelling
dc.subject.otherphotodynamic therapy
dc.subject.otherElectron
dc.subject.otherExcited state
dc.subject.otherGround state
dc.subject.otherMolecule
dc.subject.otherMulti-configurational self-consistent field
dc.subject.otherPacific Time Zone
dc.subject.otherPhotosensitizer
dc.subject.otherPorphyrin
dc.subject.otherWave function
dc.titleChapter 8 Computational Modelling of the Steps Involved in Photodynamic Therapy
dc.typechapter
oapen.identifier.doi10.5772/37654
oapen.relation.isPublishedBy09f6769d-48ed-467d-b150-4cf2680656a1
virtual.oapen_relation_isPublishedBy.publisher_nameInTechOpen
virtual.oapen_relation_isPublishedBy.publisher_websitehttps://www.intechopen.com/
oapen.relation.isPartOfBook16367fa7-4790-4d3f-9366-c00a68396f89
virtual.oapen_relation_isPartOfBook.dc_titleMolecular Photochemistry - Various Aspects
oapen.relation.isFundedBy7292b17b-f01a-4016-94d3-d7fb5ef9fb79
virtual.oapen_relation_isFundedBy.grantor_name FP7 Ideas: European Research Council
oapen.collectionEuropean Research Council (ERC)
oapen.chapternumber1
oapen.grant.number258990
oapen.grant.acronymXCHEM
oapen.grant.programFP7
oapen.remark.publicRelevant Wikipedia pages: Electron - https://en.wikipedia.org/wiki/Electron; Excited state - https://en.wikipedia.org/wiki/Excited_state; Ground state - https://en.wikipedia.org/wiki/Ground_state; Molecule - https://en.wikipedia.org/wiki/Molecule; Multi-configurational self-consistent field - https://en.wikipedia.org/wiki/Multi-configurational_self-consistent_field; Pacific Time Zone - https://en.wikipedia.org/wiki/Pacific_Time_Zone; Photosensitizer - https://en.wikipedia.org/wiki/Photosensitizer; Porphyrin - https://en.wikipedia.org/wiki/Porphyrin; Wave function - https://en.wikipedia.org/wiki/Wave_function


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