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dc.contributor.editorArechavala-Gomeza, Virginia
dc.contributor.editorGaranto, Alejandro
dc.date.accessioned2022-03-15T07:52:49Z
dc.date.available2022-03-15T07:52:49Z
dc.date.issued2022
dc.identifierONIX_20220314_9781071620106_33
dc.identifier.urihttps://library.oapen.org/handle/20.500.12657/53317
dc.description.abstractThis open access volume gathers a variety of models, delivery systems, and approaches that can be used to assess RNA technology for exploiting antisense as a therapeutic intervention. Beginning with a section on the design of antisense technology and their delivery, the book continues by covering model systems developed to evaluate efficacy, both in vivo and in vitro, as well as methods to evaluate preclinically the toxicity associated with these new potential drugs, and intellectual property considerations. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Antisense RNA Design, Delivery, and Analysis provides basic knowledge and a large collection of methods to facilitate the work of newcomers to this vibrant and expanding field. This book was conceived thanks to the network DARTER (Delivery of Antisense RNA Therapeutics). DARTER is funded by the EU Cooperation of Science and Technology (COST), which aims to enhance interaction and collaborations between researchers in Europe and other countries.
dc.languageEnglish
dc.relation.ispartofseriesMethods in Molecular Biology
dc.subject.classificationbic Book Industry Communication::M Medicine::MM Other branches of medicine::MMJ Clinical psychology::MMJT Psychotherapy
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PN Chemistry
dc.subject.classificationbic Book Industry Communication::T Technology, engineering, agriculture::TG Mechanical engineering & materials::TGM Materials science
dc.subject.otherRNA therapeutics
dc.subject.otherAntisense technology
dc.subject.otherTherapeutic design
dc.subject.otherOligonucleotides
dc.subject.otherModel systems
dc.subject.otherOligonucleotide-mediated toxicology
dc.subject.otherOpen Access
dc.titleAntisense RNA Design, Delivery, and Analysis
dc.typebook
oapen.identifier.doi10.1007/978-1-0716-2010-6
oapen.relation.isPublishedBy6c6992af-b843-4f46-859c-f6e9998e40d5
oapen.relation.isFundedByf1d9faa0-0bd1-4fe9-9e3a-99696242d3f6
oapen.relation.isbn9781071620106
oapen.imprintHumana
oapen.series.number2434
oapen.pages422
oapen.place.publicationNew York
oapen.grant.number[grantnumber unknown]


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