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dc.contributor.authorMogessie, Binyam
dc.date.accessioned2022-06-09T10:16:44Z
dc.date.available2022-06-09T10:16:44Z
dc.date.issued2019
dc.identifier.urihttps://library.oapen.org/handle/20.500.12657/56693
dc.description.abstractChromosome segregation is conserved throughout eukaryotes. In most systems, it is solely driven by a spindle machinery that is assembled from microtubules. We have recently discovered that actin filaments that are embedded inside meiotic spindles (spindle actin) are needed for accurate chromosome segregation in mammalian oocytes. To understand the function of spindle actin in oocyte meiosis, we have developed high-resolution and super-resolution live and immunofluorescence microscopy assays that are described in this chapteren_US
dc.languageEnglishen_US
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PS Biology, life sciences::PSB Biochemistryen_US
dc.subject.classificationbic Book Industry Communication::P Mathematics & science::PS Biology, life sciencesen_US
dc.subject.otherActin, Microtubules, Chromosomes, Meiosis, Oocytes, Eggs, Spindle, Fertility, High-resolution live microscopyen_US
dc.titleChapter 17 Visualization and Functional Analysis of Spindle Actin and Chromosome Segregation in Mammalian Oocytesen_US
dc.typechapter
oapen.identifier.doi10.1007/978-1-0716-0219-5_22en_US
oapen.relation.isPublishedBy8cf70738-d164-4fbe-bf04-ca83ba19c992en_US
oapen.relation.isPartOfBookf109903e-5ba3-4f5c-8b31-3f405e6b765ben_US
oapen.relation.isFundedByd859fbd3-d884-4090-a0ec-baf821c9abfden_US
oapen.relation.isbn9781071602188en_US
oapen.relation.isbn9781071602218en_US
oapen.collectionWellcomeen_US
oapen.pages29en_US


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