Show simple item record

dc.contributor.authorMattick, John
dc.contributor.authorAmaral, Paulo
dc.date.accessioned2022-07-22T12:07:10Z
dc.date.available2022-07-22T12:07:10Z
dc.date.issued2023
dc.identifierONIX_20220722_9781000623086_18
dc.identifier.urihttps://library.oapen.org/handle/20.500.12657/57585
dc.description.abstractThe origin story and emergence of molecular biology is muddled. The early triumphs in bacterial genetics and the complexity of animal and plant genomes complicate an intricate history. This book documents the many advances, as well as the prejudices and founder fallacies. It highlights the premature relegation of RNA to simply an intermediate between gene and protein, the underestimation of the amount of information required to program the development of multicellular organisms, and the dawning realization that RNA is the cornerstone of cell biology, development, brain function and probably evolution itself. Key personalities, their hubris as well as prescient predictions are richly illustrated with quotes, archival material, photographs, diagrams and references to bring the people, ideas and discoveries to life, from the conceptual cradles of molecular biology to the current revolution in the understanding of genetic information. Key Features Documents the confused early history of DNA, RNA and proteins - a transformative history of molecular biology like no other. Integrates the influences of biochemistry and genetics on the landscape of molecular biology. Chronicles the important discoveries, preconceptions and misconceptions that retarded or misdirected progress. Highlights major pioneers and contributors to molecular biology, with a focus on RNA and noncoding DNA. Summarizes the mounting evidence for the central roles of non-protein-coding RNA in cell and developmental biology. Provides a thought-provoking retrospective and forward-looking perspective for advanced students and professional researchers.
dc.languageEnglish
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSD Molecular biologyen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSF Cellular biology (cytology)en_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSA Life sciences: general issues::PSAK Genetics (non-medical)en_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSG Microbiology (non-medical)en_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciences::PSB Biochemistryen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PN Chemistry::PNN Organic chemistryen_US
dc.subject.classificationthema EDItEUR::T Technology, Engineering, Agriculture, Industrial processes::TC Biochemical engineering::TCB Biotechnologyen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciencesen_US
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PH Physics::PHV Applied physics::PHVN Biophysicsen_US
dc.subject.otherCloning
dc.subject.otherDouble Helix
dc.subject.otherGenetic Code
dc.subject.otherGenetic Engineering
dc.subject.otherGene Regulation
dc.subject.otherGenome Structure and Function
dc.titleRNA, the Epicenter of Genetic Information
dc.typebook
oapen.identifier.doi10.1201/9781003109242
oapen.relation.isPublishedBy7b3c7b10-5b1e-40b3-860e-c6dd5197f0bb
oapen.relation.isbn9781000623086
oapen.relation.isbn9781003109242
oapen.relation.isbn9780367623920
oapen.relation.isbn9780367567781
oapen.imprintCRC Press
oapen.pages400
peerreview.anonymitySingle-anonymised
peerreview.idbc80075c-96cc-4740-a9f3-a234bc2598f1
peerreview.open.reviewNo
peerreview.publish.responsibilityPublisher
peerreview.review.stagePre-publication
peerreview.review.typeProposal
peerreview.reviewer.typeInternal editor
peerreview.reviewer.typeExternal peer reviewer
peerreview.titleProposal review
oapen.review.commentsTaylor & Francis open access titles are reviewed as a minimum at proposal stage by at least two external peer reviewers and an internal editor (additional reviews may be sought and additional content reviewed as required).


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record