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    Chapter Genomes

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    Author(s)
    Harb, Omar
    Boehme, Ulrike
    Crouch, Kathryn
    Ifeonu, Olukemi
    Roos, David
    Silva, Joana
    Silva-Franco, Fatima
    Svärd, Staffan
    Tretina, Kyle
    Weedall, Gareth
    Collection
    Wellcome
    Language
    English
    Show full item record
    Abstract
    In the last decade, the rise of affordable affordable high-throughput sequencing technologies has led to rapid advances across the biological sciences. At the time of writing, annotated reference genomes are available within most clades of eukaryotic pathogens, and including un-annotated sequences over 550 genomes are available in total. This This has greatly facilitated studies in many areas of parasitology. In addition, the volume of functional genomics data, including analysis of differential differential transcription and DNA-protein interactions, has increased exponentially. With this unprecedented increase in publicly available data, tools to search and compare datasets are also becoming ever more important. A number of database resources are available, and access to these has become fundamental for a majority of research groups. This This chapter discusses the current state of genomics research for a number of eukaryotic parasites, discussing the genome and functional genomics resources available at the time of writing and highlighting functionally important or unique aspects of the genome for each group. In addition publicly accessible database resources pertaining to eukaryotic parasites are also discussed.
    Book
    Molecular Parasitology
    URI
    https://library.oapen.org/handle/20.500.12657/49611
    Keywords
    biological sciences; genomes; parasitology; genomics research; eukaryotic parasites
    ISBN
    9783709114155, 9783709148792, 9783709114162
    Publisher
    Springer Nature
    Publisher website
    https://www.springernature.com/gp/products/books
    Publication date and place
    2016
    Grantor
    • Wellcome Trust
    Classification
    Medical parasitology
    Pages
    37
    Rights
    https://creativecommons.org/licenses/by/4.0/
    • Imported or submitted locally

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    License

    • If not noted otherwise all contents are available under Attribution 4.0 International (CC BY 4.0)

    Credits

    • logo EU
    • This project received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 683680, 810640, 871069 and 964352.

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