The Faculty of Engineering was born in Florence only 50 years ago, and with Mechanical and Electronics Engineering formed the first nucleus of an area now represented by the Departments of Industrial Engineering (DIEF) and Information Engineering (DINFO). Along these 50 years, several transitions have been triggered by technological advancements, from Personal Computers, the World Wide Web and cellular telephony, to the interconnection of data and computing capabilities, integrated into industrial processes and supported by the development of transportation systems, up to the most recent challenges of artificial intelligence and energy transition. In this scenario, the University has contributed to the growth of research in the technological area, a fundamental engine for regional development towards innovation and a sustainable future.