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    Primary Adrenal Malignancies

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    Contributor(s)
    Tiberio, Guido A. M. (editor)
    Language
    English
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    Abstract
    Dissemination of knowledge is the best and only strategy capable of improving clinical management in rare and ultra-rare malignancies, including primary adrenal malignancies. It is preliminary to any further healthcare policy such as, for example, the centralization of cases in referral institutions. Adrenal primary malignancies are probably the rarest among rare pathologies. This epidemiological consideration is at the origin of a vicious circle: the lack of preoperative diagnosis leads to inappropriate surgical procedures and to inadequate follow-up and systemic therapy strategies. Furthermore, when malignancy is recognized, the relative role of systemic, surgical, or other local ablative techniques is often misinterpreted. All this produces a negative impact on survival, also in patients who could have been cured with a correct therapeutic strategy. This open access book provides a user-friendly exploration of these rare conditions, using a transversal approach common in modern precision medicine. The text covers various clinical aspects, including epidemiology, genetics, molecular medicine, imaging, and surgery. Guidelines for managing syndromic situations are provided. The book thoroughly addresses all the different surgical issues and emphasizes the importance of pathology in assessing prognosis. The pivotal role of medical oncologists in managing these patients is explored, along with alternative treatments such as nuclear medicine and radiotherapy. Finally, the book highlights the latest preclinical research and its implications for translational medicine.
    URI
    https://library.oapen.org/handle/20.500.12657/92691
    Keywords
    Adrenal Incidentaloma; Adrenocortical Carcinoma; Malignant Pheocromocytoma; Diagnosis of Adrenal Malignancies; Multimodal Management of Adrenal Malignancies
    DOI
    10.1007/978-3-031-62301-1
    ISBN
    9783031623011, 9783031623004, 9783031623011
    Publisher
    Springer Nature
    Publisher website
    https://www.springernature.com/gp/products/books
    Publication date and place
    Cham, 2025
    Imprint
    Springer Nature Switzerland
    Series
    Updates in Surgery,
    Classification
    General surgery
    Clinical and internal medicine
    Genetics (non-medical)
    Medical imaging
    Oncology
    Medical research
    Pages
    176
    Rights
    http://creativecommons.org/licenses/by-nc-nd/4.0/
    • Imported or submitted locally

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    License

    • If not noted otherwise all contents are available under Attribution 4.0 International (CC BY 4.0)

    Credits

    • logo EU
    • This project received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 683680, 810640, 871069 and 964352.

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