The scientific literature and clinical dental practice have in the extraction of the lower third molar an area of wide interest. In fact, parallel to the presence of prejudices and false beliefs on the part of patients, there is also a great variability of scientific opinions among professionals in the field, both in relation to the indications for extraction, diagnostic aids, and intra- and post-operative management. Our text aims to merge the awareness given by clinical experience with the knowledge of an evidence-based dental culture, proposing itself as a stimulus for in-depth study for students, professionals and enthusiasts of the subject. The multimedia digital resources (photos and videos) of some dental procedures can be freely consulted via the QR code on the cover or here.